Jetsun Chokyi Gyaltsan: An exalted wisdom that is able to overcome its antithetical class is the definition of antidotal knowledge aspect.
To be a path it has to counteract its antithetical affliction, such as love counteracting anger, impermanence counteracting attachment or wisdom counteracting ignorance.
To be a happy meditator, it is important that over time the meditation becomes an antidote against the afflictions, because only a lessening of these disturbing thoughts can produce the inner happiness that one is looking for. The meditation needs to hit the spot. Otherwise our meditation will drive on one side of the highway, and our delusions happily on the other side of the highway in the opposite direction, leaning out of the windows, waving and jeering at us.